MP72-20 INHIBITION OF ICAM-1 AS A NOVEL THERAPEUTIC STRATEGY IN A RAT MODEL OF NON-BACTERIAL CYSTITIS RESEMBLING INTERSTITIAL CYSTITIS.
نویسندگان
چکیده
منابع مشابه
Specific inhibition of ICAM-1 effectively reduces bladder inflammation in a rat model of severe non-bacterial cystitis
The development and progression of bladder pain syndrome/interstitial cystitis (BPS/IC) is closely related to bladder inflammation. Intercellular adhesion molecule 1 (ICAM-1) is associated with bladder inflammation in BPS/IC. We investigated the effect of specific inhibition of ICAM-1 using an anti-ICAM-1 antibody (AIA) on bladder inflammation in a rat model of severe non-bacterial cystitis (NB...
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Interstitial cystitis.
Deborah L. Myers, MD Interstitial cystitis (IC) is a chronic condition of urinary urgency, frequency, and suprapubic pain in the absence of bacteruria. It is part of the painful bladder syndrome whose known causes are tuberculosis, stones, malignancy, previous chemotherapy of the bladder, and pelvic radiation. Interstitial cystitis is a diagnosis of exclusion when no known cause of painful bla...
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Interstitial cystitis, described for many years, remains a mystery for several reasons. Although the clinical and therapeutic understanding of this disease have improved, the histological features are non-specific and the pathogenesis is still unclear. The aim of this article is to briefly review the current state of knowledge and to remind the reader that this disease must not be underestimate...
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ژورنال
عنوان ژورنال: Journal of Urology
سال: 2016
ISSN: 0022-5347,1527-3792
DOI: 10.1016/j.juro.2016.02.1633